个人信息
1. 科研项目
[1] 国家自然科学基金面上项目,活细胞线粒体比例荧光超分辨成像研究,在研。
[2] 深圳市自然科学基金自由探索项目,活细胞线粒体的荧光标记及超分辨成像研究,在研。
[3] 国家自然科学基金青年项目,基于肿瘤缺氧调控的药物靶向释放与荧光 成像研究,已结题。
[4] 深圳市海外高层次人才“孔雀C类“计划,超分辨成像及其功能强化研究,已结题。2. 代表性学术论文
[1] W. Li, M. Huang, Y. Li, J. Qu, Z. Yang*, Novel Asymmetric D-π-A-D Type AIEgens Based Nanoparticles as Efficient 1O2 Photosensitizer and Bright NIR Imaging Agent. Dyes and Pigments, 2021,186, 109041.
[2] S. Samanta, M. Huang, S. Li, Z. Yang, L. Liu, Y. He, Z. Gu, J. Zhang, D. Zhang, J. Qu*. AIE-Active two-photon fluorescent nanoprobe with NIR-II light excitability for highly efficient deep brain vasculature imaging. Theranostics 2020, 11(5), 2137-2148.
[3] S. Samanta, M. Huang, F. Lin, Z. Yang, W. Yan, J.-J. Chen, K. Ji, L. Liu and J. Qu, Solo smart fluorogenic probe for potential cancer diagnosis and tracking in vivo tumorous lymphatic systems via distinct emission signals, Analytical Chemistry, 2020, 92(1), 1541- 1548
[4] W. Li, W. Pan, M.Huang, Z. Yang, Y. He, W. Zhang, W. Yan, and J. Qu, Nanoscopic imaging of mitochondrial dynamics with an in situ photoblinking-activated probe in live cells, Analytical Chemistry, 2021, 93, 4, 2596–2602.
[5] W. Zhang, S. Li, Z. Yang, B. Yu, D. Lin, W. Yan, J. Li, L. Wang, J. Xiong and J. Qu, Virtual single-pixel imaging-based deconvolution method for spatial resolution improvement in wide-field fluorescence microscopy, Biomedical Optics Express, 2020, 11(7), 3648-3658.
[6] B. Chen, W. Gong, Z. Yang, W. Pan, W. Yan, L. Liu, and J. Qu and J. S. Kim, STORM imaging of mitochondrial dynamics using a vicinal-dithiol-proteins-targeted probe, Biomaterials, 2020, 243, 119938.
[7] X. Yang, Z. Yang, Z. Wu, Y. He, C. Shan, P. Chai, J. Teng, M. Tian, C. Ma, W. Yan, P. Das, J. Qu and P. Xi, Mitochondrial dynamics quantitatively revealed by STED nanoscopy with an enhanced squaraine variant probe, Nature Communications, 2020, 11, 3699.
[8] S. Samanta, Y. He, A. Sharma, J. Kim, W. Pan, Z. Yang, J. Li, W. Yan, L. Liu, J. Qu, J. S. Kim, Fluorescent Probes for Nanoscopic Imaging of Mitochondria, CHEM, 2019, 5(7), 1697-1726.
[9] Z. Yang, A. Sharma, J. Qi, X. Peng, D. Y. Lee, R. Hu, D. Lin, J. Qu and J. S. Kim*, Super-resolution fluorescent materials: an insight into design and bioimaging applications, Chemical Society Reviews, 2016, 45, 4651-4667.
[10] Z. Yang, J. H. Lee, H. Mi, J. H. Han, N. Park, Y. He, H. Lee, K. S.Hong, C. Kang, and J. S. Kim, Folate-based Near-Infrared fluorescent theranostic gemicitabine delivery; J. Am. Chem. Soc. 2013, 135, 11657-11662.3. 代表性发明专利
[1] 杨志刚*,张建国,顾振宇,屈军乐,一种应用于活细胞的超分辨随机光学重构显微成 像系统,中国发明专利 (202010866712.7) 申请日期:2020.08.25
[2] 杨志刚*,顾振宇,张建国,屈军乐,一种可穿戴式多模态装置及成像方法,中国发明 专利(202010099239.4) 申请日期:2020.02.18;实用新型专利(ZL202020182288.X)
[3] 杨志刚*,屈军乐,荧光染料及其制备方法和应用,中国发明专利(201711388815.1); PCT专利 (PCT/CN2017/117597); 美国专利(US10889719B2);欧洲发明专利 (17935203.4)
[4] 杨志刚*,屈军乐,刘毋凡,一种五甲川菁染料及制备方法,(201810018423.4);PCT专 利 (PCT/CN2018/071901);美国专利(US16667864)
[5] 杨志刚*,刘毋凡,屈军乐; 一种超分辨成像方法、装置及终端设备;中国发明专利 (201810958217.1)
[6] 杨志刚*,张炜,陈楚芳,屈军乐;一种图像重构方法、装置、电子设备和存储介质; 中国发明专利(201810982770 .9)
[7] 杨志刚*,李文,潘文慧,熊佳,屈军乐;五甲川菁染料及其制备方法,中国发明专利 (201910213697.3)
[8] 屈军乐,陈秉灵,潘文慧,杨志刚; 分子定位超分辨成像的降噪方法、装置及终端设备; 中国发明专利(201811055949.6)4. 办公地址: 深圳大学沧海校区致原楼715B.
5. 联系方式:zhgyang@szu.edu.cn